Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

• Ketoconazole, itraconazole (used to manage fungal infection)
• Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
• Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
• Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
• Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

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If you experience any side effects or experience severe side effects, such as trouble urinating, or you are experiencing yellowing of the skin or eyes, seek medical attention.

C.

Cialis (tadalafil) can interact with certain foods and beverages, including grapefruit, grapefruit, and grapefruit juice. Fungal infections like tinea corporis, tinea cruris, and tinea pedis can all occur with similar dosages. If you experience symptoms of both T. pedis and T. diphtheria can occur by lying down immediately after taking Cialis or engaging in soothing exercises, such as walking distance from the infected area, or by spreading the infection to other areas of the body. Avoid and use with Cialis on caution, as it can increase the levels of tadalafil in your blood.

D.

Cialis medicine is manufactured by Lupin. Cialis is available in 20mg. Cialis medicine contains generic salt Content Tadalafil. This medicine used to help Treatment of Erectile DysfunctionDetails- 1. Brand name – Cialis 2. Generic – Tadalafil3. Dosage form – tablet4. Used – It is used to help Treatment of Erectile Dysfunction 5. Packaging – 4 tablets6. Strength – 20mg7. Manufactured & Marketed By – LupinWe are exporters & wholesalers of Cialis Medicine. Cialis medicine is available at discounted prices. We can provide the best price for Cialis. We export Cialis medicine to China, USA, London, Europe, Thailand, Russia, Malaysia, Singapore, Vietnam, Dubai. Warning: Cialis Medicine out of the reach and sight of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. ATTENTION - Above mention price only for reference. If you wish to know about best discounted price or order of any kind of medicine than you just contact us as soon as possible. Please check our contact us page for complete details. Cialis is a prescription drug and should be used under proper medical guidance and advice. Do not share the medicine with others, since they may be suffering from a problem that is not effectively treated by this drug.• Keep all medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.• The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you. Before eating/consuming any medicine kindly do consult with your doctor / Medical adviser / Nurse / Hospital /medicine Institution / Health advisor or pharmacist/ medicine healer. Do not indulge in self medication using internet information. Self medication can be dangerous.

MEDICINAL RESOURCES

Self medication using online pharmacies like Drugs.com can lead to dangerous side effects, so you should avoid using them unless advised by a medical adviser, health advisor or medicines healer.• Do not exceed the prescribed dosage.• If you forgot to take your dose to be taken, take it as soon as you remember. If you do not remember until the following week, take a new dose and continue with your regular schedule. If you remember about it, take it as soon as you remember.• If you have any health concerns, contact your doctor / prescriber / your doctor / nurse / pharmacist / health advisor / your pharmacist / medical adviser / hospital / health professional / your doctor / nursing / hospital / health advisor / your doctor / or nurse before using this medication. Lerner Laboratories, Inc. can cause harmful side effects, so you should consult your doctor before using this medication. Please seek medical advice or advice from your doctor / pharmacist before using this medication. Self medication using online pharmacies like Drugs.com can lead to dangerous side effects, so you should avoid using them unless advised by a medical adviser, health advisor or medicines healer.

What Is Tadalafil Tablets in Pakistan?

Tadalafil Tablets in Pakistanis used to treat erectile dysfunction (ED) in men. It helps to improve blood flow to the penis, making it easier to get and maintain an erection.

How does Tadalafil Tablets work?

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. PDE5 inhibitors are phosphodiesterase type 5 (PDE5) inhibitors. They work by preventing the PDE5 enzyme from breaking down a substance called cyclic guanosine monophosphate (cGMP). cGMP is a naturally occurring chemical that helps to relax the smooth muscles of the blood vessels. When cGMP is released, it relaxes the arteries, which allows more blood to flow through to the penis. This helps you achieve and maintain an erection during sexual stimulation.

How to take Tadalafil Tablets in Pakistan?

Take this medication by mouth once a day. Take it as prescribed by your doctor. Your doctor may occasionally change your dose to adjust the dose of medication.

How long does Tadalafil take to work?

Tadalafil lasts for about 6-8 hours before it starts working and continues working for about 4-6 hours. Tadalafil is usually effective for approximately 4-6 hours.

Do not take Tadalafil Tablets if:

• you are allergic to any ingredient in Tadalafil Tablets, or any other ingredient of this medication
• you have had a heart attack within the last 6 months
• you have low blood pressure that is not a problem for you to treat with Tadalafil Tablets or any nitrate medication such as nitroglycerin

Before You Start Taking Tadalafil Tablets

Before You Start Taking Tadalafil Tablets inform your doctor about any medical conditions or allergies you may have, including:

• diabetes
• liver problems
• kidney problems
• heart problems or swelling in your ankles or feet
• high blood pressure
• swelling in your feet, ankles or legs
• uncontrolled or uncontrolled eye disease
• infections
• if you have anemia or leukopenia

How Tadalafil Tablets may interact with Your Medical History

Tell your doctor about all the medicines you are taking, including any that you have ever taken. Tadalafil and alcohol may cause side effects. Tadalafil may interact with Nitrates, Some Recreational Drugs, Alcohol, Alcohol Interaction Drugs, PDE5 Inhibitors, Other Medicines, etc.

Your doctor and/or pharmacist can tell you how much Tadalafil Tablets should be taken.

Your doctor and pharmacist can give you the most complete medicine list and other information. Tadalafil Tablets may make your blood pressure worse, so you may experience other side effects. Tadalafil Tablets may make your blood carry a warning sign that you have a problem with your blood pressure. You may be at risk for getting a heart attack or a stroke while taking this medication.

Tadalafil Tablets may also interact with certain medications, so it is important to inform your doctor about any you have been previously taking. Tell your doctor if you are taking any of the following:

• medicines that lower the effectiveness of Tadalafil Tablets (e.g., nitrates, certain drugs that lower blood pressure).
• medicines that reduce the effectiveness of Tadalafil Tablets (e.g., nitrates, certain drugs that lower blood pressure).
• medicines that interact with certain medications, such as certain antihistamines, certain antidepressants, some HIV medications, some antibiotics, some HIV medicines, some blood pressure medications, some antibiotics, and some antibiotics Interaction Drug Interaction Drug

This does not apply to all medications.

Sold and Supplied by Healthylife Pharmacy

Generic Tadalafil (20mg) 8 Tablets

This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.

Healthylife provides general product information such as nutritional information, country of origin and product packaging for your convenience. This information is intended as a guide only, including because products change from time to time. Please read product labels before consuming. For therapeutic goods, always read the label and follow the directions for use on pack. If you require specific information to assist with your purchasing decision, we recommend that you contact the manufacturer via the contact details on the packaging or email us at [email protected]. Product ratings and reviews are taken from various sources including Bazaarvoice. Healthylife does not represent or warrant the accuracy of any statements, claims or opinions made in product ratings and reviews.

PACKAGE TAB>Product NameHealthylife Pharmacy, an independently-owned and operated pharmacy business

Healthylife provides generic tadalafil (20mg) 8 tablets for use with as necessary in patients with erectile dysfunction. The generic is brand name Cialis. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction. Erectile dysfunction is the inability to sustain a hard and erect penis sufficient for satisfactory sexual activity. Tadalafil belongs to a class of drugs known as PDE5 inhibitors. It works by relaxing the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited, causing an erection. Cialis is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction. Erectile dysfunction is the inability to maintain a hard and erect penis sufficient for satisfactory sexual activity. It works by relaxing the blood vessels in your penis, allowing blood to flow into your penis causing an erection. Cialis is a phosphodiesterase (PDE5) inhibitor used to treat erectile dysfunction. Tadalafil is a PDE5 inhibitor used to treat erectile dysfunction. Tadalafil is a phosphodiesterase (PDE5) inhibitor used to treat erectile dysfunction.

References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.